Folic Acid Inhibits Amyloid β-Peptide Production through Modulating DNA Methyltransferase Activity in N2a-APP Cells

Alzheimer’s disease (AD) is a common neurodegenerative disease resulting in progressive dementia, and is a principal cause of dementia among older adults. Folate acts through one-carbon metabolism to support the methylation of multiple substrates. We hypothesized that folic acid supplementation modu...

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Detalles Bibliográficos
Autores principales: Li, Wen, Jiang, Mingyue, Zhao, Shijing, Liu, Huan, Zhang, Xumei, Wilson, John X., Huang, Guowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632786/
https://www.ncbi.nlm.nih.gov/pubmed/26492244
http://dx.doi.org/10.3390/ijms161025002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632786/
https://www.ncbi.nlm.nih.gov/pubmed/26492244
http://dx.doi.org/10.3390/ijms161025002

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