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Folic Acid Inhibits Amyloid β-Peptide Production through Modulating DNA Methyltransferase Activity in N2a-APP Cells
Alzheimer’s disease (AD) is a common neurodegenerative disease resulting in progressive dementia, and is a principal cause of dementia among older adults. Folate acts through one-carbon metabolism to support the methylation of multiple substrates. We hypothesized that folic acid supplementation modu...
Autores principales: | Li, Wen, Jiang, Mingyue, Zhao, Shijing, Liu, Huan, Zhang, Xumei, Wilson, John X., Huang, Guowei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632786/ https://www.ncbi.nlm.nih.gov/pubmed/26492244 http://dx.doi.org/10.3390/ijms161025002 |
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