Cargando…

Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin

Recent successes of adeno-associated virus (AAV)–based gene therapy have created a demand for large-scale AAV vector manufacturing and purification techniques for use in clinical trials and beyond. During the development of purification protocols for rh.10, hu.37, AAV8, rh.64R1, AAV3B, and AAV9 vect...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Qiang, Lock, Martin, Prongay, Andrew J, Alvira, Mauricio R, Petkov, Boris, Wilson, James M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632836/
https://www.ncbi.nlm.nih.gov/pubmed/26605372
http://dx.doi.org/10.1038/mtm.2015.40