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Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin

Recent successes of adeno-associated virus (AAV)–based gene therapy have created a demand for large-scale AAV vector manufacturing and purification techniques for use in clinical trials and beyond. During the development of purification protocols for rh.10, hu.37, AAV8, rh.64R1, AAV3B, and AAV9 vect...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Lock, Martin, Prongay, Andrew J, Alvira, Mauricio R, Petkov, Boris, Wilson, James M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632836/
https://www.ncbi.nlm.nih.gov/pubmed/26605372
http://dx.doi.org/10.1038/mtm.2015.40

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