Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis

Chronic pancreatitis (CP) is a progressive and irreversible inflammatory and fibrotic disease with no cure. Unlike acute pancreatitis, we find that alternatively activated macrophages (AAMs) are dominant in mouse and human CP. AAMs are dependent on IL-4 and IL-13 signaling and we show that mice lack...

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Detalles Bibliográficos
Autores principales: Xue, Jing, Sharma, Vishal, Hsieh, Michael H., Chawla, Ajay, Murali, Ramachandran, Pandol, Stephen J., Habtezion, Aida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632846/
https://www.ncbi.nlm.nih.gov/pubmed/25981357
http://dx.doi.org/10.1038/ncomms8158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632846/
https://www.ncbi.nlm.nih.gov/pubmed/25981357
http://dx.doi.org/10.1038/ncomms8158

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