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Decreased expression of 14-3-3 σ, an early event of malignant transformation of respiratory epithelium, also facilitates progression of squamous cell lung cancer

BACKGROUND: It has been shown that 14-3-3 σ serves as a tumor suppressor gene, and is downregulated in various tumor tissues. However, the role of 14-3-3 σ during the initiation and progression of lung squamous cell carcinoma (SqCC) is not well understood. METHODS: The expression status of 14-3-3 σ...

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Detalles Bibliográficos
Autores principales: Sun, Nan, Wu, Yongkai, Huang, Bo, Liu, Qian, Dong, Yinan, Ding, Jianqiao, Liu, Yongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632923/
https://www.ncbi.nlm.nih.gov/pubmed/26557909
http://dx.doi.org/10.1111/1759-7714.12246