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Targeting N-Glycan Cryptic Sugar Moieties for Broad-Spectrum Virus Neutralization: Progress in Identifying Conserved Molecular Targets in Viruses of Distinct Phylogenetic Origins

Identifying molecular targets for eliciting broadly virus-neutralizing antibodies is one of the key steps toward development of vaccines against emerging viral pathogens. Owing to genomic and somatic diversities among viral species, identifying protein targets for broad-spectrum virus neutralization...

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Detalles Bibliográficos
Autores principales: Wang, Denong, Tang, Jin, Tang, Jiulai, Wang, Lai-Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633014/
https://www.ncbi.nlm.nih.gov/pubmed/25774492
http://dx.doi.org/10.3390/molecules20034610