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Regulation of Guinea Pig Detrusor Smooth Muscle Excitability by 17β-Estradiol: The Role of the Large Conductance Voltage- and Ca(2+)-Activated K(+) Channels

Estrogen replacement therapies have been suggested to be beneficial in alleviating symptoms of overactive bladder. However, the precise regulatory mechanisms of estrogen in urinary bladder smooth muscle (UBSM) at the cellular level remain unknown. Large conductance voltage- and Ca(2+)-activated K(+)...

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Detalles Bibliográficos
Autores principales: Provence, Aaron, Hristov, Kiril L., Parajuli, Shankar P., Petkov, Georgi V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633058/
https://www.ncbi.nlm.nih.gov/pubmed/26536038
http://dx.doi.org/10.1371/journal.pone.0141950