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Direct Measurements of Local Coupling between Myosin Molecules Are Consistent with a Model of Muscle Activation
Muscle contracts due to ATP-dependent interactions of myosin motors with thin filaments composed of the proteins actin, troponin, and tropomyosin. Contraction is initiated when calcium binds to troponin, which changes conformation and displaces tropomyosin, a filamentous protein that wraps around th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633106/ https://www.ncbi.nlm.nih.gov/pubmed/26536123 http://dx.doi.org/10.1371/journal.pcbi.1004599 |