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FL3, a Synthetic Flavagline and Ligand of Prohibitins, Protects Cardiomyocytes via STAT3 from Doxorubicin Toxicity

AIMS: The clinical use of doxorubicin for the treatment of cancer is limited by its cardiotoxicity. Flavaglines are natural products that have both potent anticancer and cardioprotective properties. A synthetic analog of flavaglines, FL3, efficiently protects mice from the cardiotoxicity of doxorubi...

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Detalles Bibliográficos
Autores principales:	Qureshi, Rehana, Yildirim, Onur, Gasser, Adeline, Basmadjian, Christine, Zhao, Qian, Wilmet, Jean-Philippe, Désaubry, Laurent, Nebigil, Canan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633129/ https://www.ncbi.nlm.nih.gov/pubmed/26536361 http://dx.doi.org/10.1371/journal.pone.0141826

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