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Inositol Polyphosphate-4-Phosphatase Type I Negatively Regulates Phagocytosis via Dephosphorylation of Phagosomal PtdIns(3,4)P(2)

Phagocytosis is a highly conserved process whereby phagocytic cells engulf pathogens and apoptotic bodies. The present study focused on the role of inositol polyphosphate-4-phosphatase type I (Inpp4a) in phagocytosis. Raw264.7 cells that express shRNA against Inpp4a (shInpp4a cells) showed significa...

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Detalles Bibliográficos
Autores principales: Nigorikawa, Kiyomi, Hazeki, Kaoru, Sasaki, Junko, Omori, Yumio, Miyake, Mikiko, Morioka, Shin, Guo, Ying, Sasaki, Takehiko, Hazeki, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633150/
https://www.ncbi.nlm.nih.gov/pubmed/26535897
http://dx.doi.org/10.1371/journal.pone.0142091