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Inositol Polyphosphate-4-Phosphatase Type I Negatively Regulates Phagocytosis via Dephosphorylation of Phagosomal PtdIns(3,4)P(2)
Phagocytosis is a highly conserved process whereby phagocytic cells engulf pathogens and apoptotic bodies. The present study focused on the role of inositol polyphosphate-4-phosphatase type I (Inpp4a) in phagocytosis. Raw264.7 cells that express shRNA against Inpp4a (shInpp4a cells) showed significa...
Autores principales: | Nigorikawa, Kiyomi, Hazeki, Kaoru, Sasaki, Junko, Omori, Yumio, Miyake, Mikiko, Morioka, Shin, Guo, Ying, Sasaki, Takehiko, Hazeki, Osamu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633150/ https://www.ncbi.nlm.nih.gov/pubmed/26535897 http://dx.doi.org/10.1371/journal.pone.0142091 |
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