A novel MeCP2 acetylation site regulates interaction with ATRX and HDAC1

Methyl-CpG-binding protein-2 (MeCP2) regulates gene expression by recruiting SWI/SNF DNA helicase/ATPase (ATRX) and Histone Deacetylase-1 (HDAC1) to methylated gene regions and modulates heterochromatin association by interacting with Heterochromatin protein-1. As MeCP2 contributes to tumor suppress...

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Detalles Bibliográficos
Autores principales: Pandey, Somnath, Simmons, Glenn E., Malyarchuk, Svitlana, Calhoun, Tara N., Pruitt, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633168/
https://www.ncbi.nlm.nih.gov/pubmed/26622943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633168/
https://www.ncbi.nlm.nih.gov/pubmed/26622943

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