Cargando…

Effect of C-Terminal S-Palmitoylation on D2 Dopamine Receptor Trafficking and Stability

We have used bioorthogonal click chemistry (BCC), a sensitive non-isotopic labeling method, to analyze the palmitoylation status of the D2 dopamine receptor (D2R), a G protein-coupled receptor (GPCR) crucial for regulation of processes such as mood, reward, and motor control. By analyzing a series o...

Descripción completa

Detalles Bibliográficos
Autores principales: Ebersole, Brittany, Petko, Jessica, Woll, Matthew, Murakami, Shoko, Sokolina, Kate, Wong, Victoria, Stagljar, Igor, Lüscher, Bernhard, Levenson, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633242/
https://www.ncbi.nlm.nih.gov/pubmed/26535572
http://dx.doi.org/10.1371/journal.pone.0140661