Constitutive control of AKT-1 gene expression by JUNB / CJUN in ALK+ anaplastic large cell lymphoma: a novel crosstalk mechanism

Anaplastic lymphoma kinase-positive (ALK+) anaplastic large cell lymphoma (ALCL) is an aggressive T-cell non-Hodgkin lymphoma characterized by the t(2;5) resulting in overexpression of NPM-ALK, which is known to activate the phosphatidylinositol-3-kinase (PI3K)/AKT/mTOR pathway resulting in cell cyc...

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Detalles Bibliográficos
Autores principales: Atsaves, Vassilios, Zhang, Ronghua, Ruder, Dennis, Pan, Yunbao, Leventaki, Vasiliki, Rassidakis, George Z., Claret, Francois X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633353/
https://www.ncbi.nlm.nih.gov/pubmed/25987255
http://dx.doi.org/10.1038/leu.2015.127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633353/
https://www.ncbi.nlm.nih.gov/pubmed/25987255
http://dx.doi.org/10.1038/leu.2015.127

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