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Combined Tumor Cell-Based Vaccination and Interleukin-12 Gene Therapy Polarizes the Tumor Microenvironment in Mice

Tumor progression depends on tumor milieu, which influences neovasculature formation and immunosuppression. Combining immunotherapy with antiangiogenic/antivascular therapy might be an effective therapeutic approach. The aim of our study was to elaborate an anticancer therapeutic strategy based on t...

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Detalles Bibliográficos
Autores principales: Jarosz-Biej, Magdalena, Smolarczyk, Ryszard, Cichoń, Tomasz, Kułach, Natalia, Czapla, Justyna, Matuszczak, Sybilla, Szala, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633448/
https://www.ncbi.nlm.nih.gov/pubmed/25801067
http://dx.doi.org/10.1007/s00005-015-0337-y