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N-myc downstream regulated gene 2 overexpression reduces matrix metalloproteinase-2 and -9 activities and cell invasion of A549 lung cancer cell line in vitro

OBJECTIVE(S): N-myc downstream regulated gene 2 (NDRG2) is a candidate gene for tumor suppression. The expression of NDRG2 is down-regulated in several tumors including lung cancer. The aim of this study was to explore the effect of NDRG2 overexpression on invasion, migration, and enzymatic activity...

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Detalles Bibliográficos
Autores principales: Faraji, Seyed Nooredin, Mojtahedi, Zahra, Ghalamfarsa, Ghasem, Takhshid, Mohammad Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633460/
https://www.ncbi.nlm.nih.gov/pubmed/26557966