Conformational selection and induced fit for RNA polymerase and RNA/DNA hybrid backtracked recognition

RNA polymerase catalyzes transcription with a high fidelity. If DNA/RNA mismatch or DNA damage occurs downstream, a backtracked RNA polymerase can proofread this situation. However, the backtracked mechanism is still poorly understood. Here we have performed multiple explicit-solvent molecular dynam...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Jian, Ye, Wei, Yang, Jingxu, Chen, Hai-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633505/
https://www.ncbi.nlm.nih.gov/pubmed/26594643
http://dx.doi.org/10.3389/fmolb.2015.00061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633505/
https://www.ncbi.nlm.nih.gov/pubmed/26594643
http://dx.doi.org/10.3389/fmolb.2015.00061

Ejemplares similares