Targeting the Nuclear Export Protein XPO1/CRM1 Reverses Epithelial to Mesenchymal Transition

Here we demonstrate for the first time that targeted inhibition of nuclear exporter protein exportin 1 (XPO1) also known as chromosome maintenance region 1 (CRM1) by Selective Inhibitor of Nuclear Export (SINE) compounds results in reversal of EMT in snail-transduced primary human mammary epithelial...

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Detalles Bibliográficos
Autores principales: Azmi, Asfar S., Muqbil, Irfana, Wu, Jack, Aboukameel, Amro, Senapedis, William, Baloglu, Erkan, Bollig-Fischer, Aliccia, Dyson, Gregory, Kauffman, Michael, Landesman, Yosef, Shacham, Sharon, Philip, Philip A., Mohammad, Ramzi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633607/
https://www.ncbi.nlm.nih.gov/pubmed/26536918
http://dx.doi.org/10.1038/srep16077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633607/
https://www.ncbi.nlm.nih.gov/pubmed/26536918
http://dx.doi.org/10.1038/srep16077

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