IDH mutation status is associated with a distinct hypoxia/angiogenesis transcriptome signature which is non-invasively predictable with rCBV imaging in human glioma

The recent identification of IDH mutations in gliomas and several other cancers suggests that this pathway is involved in oncogenesis; however effector functions are complex and yet incompletely understood. To study the regulatory effects of IDH on hypoxia-inducible-factor 1-alpha (HIF1A), a driving...

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Detalles Bibliográficos
Autores principales: Kickingereder, Philipp, Sahm, Felix, Radbruch, Alexander, Wick, Wolfgang, Heiland, Sabine, Deimling, Andreas von, Bendszus, Martin, Wiestler, Benedikt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633672/
https://www.ncbi.nlm.nih.gov/pubmed/26538165
http://dx.doi.org/10.1038/srep16238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633672/
https://www.ncbi.nlm.nih.gov/pubmed/26538165
http://dx.doi.org/10.1038/srep16238

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