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Direct optical activation of skeletal muscle fibres efficiently controls muscle contraction and attenuates denervation atrophy

Neural prostheses can restore meaningful function to paralysed muscles by electrically stimulating innervating motor axons, but fail when muscles are completely denervated, as seen in amyotrophic lateral sclerosis, or after a peripheral nerve or spinal cord injury. Here we show that channelrhodopsin...

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Detalles Bibliográficos
Autores principales: Magown, Philippe, Shettar, Basavaraj, Zhang, Ying, Rafuse, Victor F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633712/
https://www.ncbi.nlm.nih.gov/pubmed/26460719
http://dx.doi.org/10.1038/ncomms9506