Membrane stiffening by STOML3 facilitates mechanosensation in sensory neurons

Sensing force is crucial to maintain the viability of all living cells. Despite its fundamental importance, how force is sensed at the molecular level remains largely unknown. Here we show that stomatin-like protein-3 (STOML3) controls membrane mechanics by binding cholesterol and thus facilitates f...

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Detalles Bibliográficos
Autores principales: Qi, Yanmei, Andolfi, Laura, Frattini, Flavia, Mayer, Florian, Lazzarino, Marco, Hu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633829/
https://www.ncbi.nlm.nih.gov/pubmed/26443885
http://dx.doi.org/10.1038/ncomms9512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633829/
https://www.ncbi.nlm.nih.gov/pubmed/26443885
http://dx.doi.org/10.1038/ncomms9512

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