Cargando…
Membrane stiffening by STOML3 facilitates mechanosensation in sensory neurons
Sensing force is crucial to maintain the viability of all living cells. Despite its fundamental importance, how force is sensed at the molecular level remains largely unknown. Here we show that stomatin-like protein-3 (STOML3) controls membrane mechanics by binding cholesterol and thus facilitates f...
Autores principales: | Qi, Yanmei, Andolfi, Laura, Frattini, Flavia, Mayer, Florian, Lazzarino, Marco, Hu, Jing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633829/ https://www.ncbi.nlm.nih.gov/pubmed/26443885 http://dx.doi.org/10.1038/ncomms9512 |
Ejemplares similares
-
A Role for STOML3 in Olfactory Sensory Transduction
por: Agostinelli, Emilio, et al.
Publicado: (2021) -
Regulation of ASIC channels by a stomatin/STOML3 complex located in a mobile vesicle pool in sensory neurons
por: Lapatsina, Liudmila, et al.
Publicado: (2012) -
Inflammatory Cytokines Alter Mesenchymal Stem Cell Mechanosensing and Adhesion on Stiffened Infarct Heart Tissue After Myocardial Infarction
por: Zhu, Dan, et al.
Publicado: (2020) -
Cholesterol Stiffening of Lipid Membranes
por: Doole, Fathima T., et al.
Publicado: (2022) -
Polarity of varicosity initiation in central neuron mechanosensation
por: Gu, Yuanzheng, et al.
Publicado: (2017)