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A steroid metabolizing gene variant in a polyfactorial model improves risk prediction in a high incidence breast cancer population
BACKGROUND: We have combined functional gene polymorphisms with clinical factors to improve prediction and understanding of sporadic breast cancer risk, particularly within a high incidence Caucasian population. METHODS: A polyfactorial risk model (PFRM) was built from both clinical data and functio...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633888/ https://www.ncbi.nlm.nih.gov/pubmed/26673457 http://dx.doi.org/10.1016/j.bbacli.2014.11.001 |