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Molecular profiling of childhood cancer: Biomarkers and novel therapies

BACKGROUND: Technological advances including high-throughput sequencing have identified numerous tumor-specific genetic changes in pediatric and adolescent cancers that can be exploited as targets for novel therapies. SCOPE OF REVIEW: This review provides a detailed overview of recent advances in th...

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Detalles Bibliográficos
Autores principales: Saletta, Federica, Wadham, Carol, Ziegler, David S., Marshall, Glenn M., Haber, Michelle, McCowage, Geoffrey, Norris, Murray D., Byrne, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633945/
https://www.ncbi.nlm.nih.gov/pubmed/26675306
http://dx.doi.org/10.1016/j.bbacli.2014.06.003