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Enhancer repertoires are reshaped independently of early priming and heterochromatin dynamics during B cell differentiation

A widely accepted model posits that activation of enhancers during differentiation goes through a priming step prior to lineage commitment. To investigate the chronology of enhancer repertoire establishment during hematopoiesis, we monitored epigenome dynamics during three developmental stages repre...

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Detalles Bibliográficos
Autores principales: Choukrallah, Mohamed-Amin, Song, Shuang, Rolink, Antonius G., Burger, Lukas, Matthias, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633987/
https://www.ncbi.nlm.nih.gov/pubmed/26477271
http://dx.doi.org/10.1038/ncomms9324