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Enhancer repertoires are reshaped independently of early priming and heterochromatin dynamics during B cell differentiation
A widely accepted model posits that activation of enhancers during differentiation goes through a priming step prior to lineage commitment. To investigate the chronology of enhancer repertoire establishment during hematopoiesis, we monitored epigenome dynamics during three developmental stages repre...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633987/ https://www.ncbi.nlm.nih.gov/pubmed/26477271 http://dx.doi.org/10.1038/ncomms9324 |