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IRSp53 senses negative membrane curvature and phase separates along membrane tubules
BAR domain proteins contribute to membrane deformation in diverse cellular processes. The inverted-BAR (I-BAR) protein IRSp53, for instance, is found on the inner leaflet of the tubular membrane of filopodia; however its role in the formation of these structures is incompletely understood. Here we d...
Autores principales: | Prévost, Coline, Zhao, Hongxia, Manzi, John, Lemichez, Emmanuel, Lappalainen, Pekka, Callan-Jones, Andrew, Bassereau, Patricia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634128/ https://www.ncbi.nlm.nih.gov/pubmed/26469246 http://dx.doi.org/10.1038/ncomms9529 |
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