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Potency under pressure: the impact of hydrostatic pressure on antigenic properties of influenza virus hemagglutinin

BACKGROUND: Influenza vaccines are effective in protecting against illness and death caused by this seasonal pathogen. The potency of influenza vaccines is measured by single radial immunodiffusion (SRID) assay that quantifies antigenic forms of hemagglutinin (HA). Hydrostatic pressure results in lo...

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Detalles Bibliográficos
Autores principales: Eichelberger, Schafer L., Sultana, Ishrat, Gao, Jin, Getie‐Kebtie, Melkamu, Alterman, Michail, Eichelberger, Maryna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634276/
https://www.ncbi.nlm.nih.gov/pubmed/23496824
http://dx.doi.org/10.1111/irv.12102