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Towards a general diastereoselective route to oxabicyclo[3.2.1]octanes via a gold-catalysed cascade reaction

The development of an efficient diastereoselective synthesis of the oxabicyclo[3.2.1]octane ring system bearing two oxygenated quaternary chiral centres represents a significant challenge. This motif can be found in a wide range of natural products with significant biological activities. Here we rep...

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Detalles Bibliográficos
Autores principales: Fu, Junkai, Gu, Yueqing, Yuan, Hao, Luo, Tuoping, Liu, Song, Lan, Yu, Gong, Jianxian, Yang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634332/
https://www.ncbi.nlm.nih.gov/pubmed/26509323
http://dx.doi.org/10.1038/ncomms9617