Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins

Phagocytosis is responsible for the elimination of particles of widely disparate sizes, from large fungi or effete cells to small bacteria. Though superficially similar, the molecular mechanisms involved differ: engulfment of large targets requires phosphoinositide 3-kinase (PI3K), while that of sma...

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Detalles Bibliográficos
Autores principales: Schlam, Daniel, Bagshaw, Richard D., Freeman, Spencer A., Collins, Richard F., Pawson, Tony, Fairn, Gregory D., Grinstein, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634337/
https://www.ncbi.nlm.nih.gov/pubmed/26465210
http://dx.doi.org/10.1038/ncomms9623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634337/
https://www.ncbi.nlm.nih.gov/pubmed/26465210
http://dx.doi.org/10.1038/ncomms9623

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