Cargando…

Multi-level omics analysis in a murine model of dystrophin loss and therapeutic restoration

Duchenne muscular dystrophy (DMD) is a classical monogenic disorder, a model disease for genomic studies and a priority candidate for regenerative medicine and gene therapy. Although the genetic cause of DMD is well known, the molecular pathogenesis of disease and the response to therapy are incompl...

Descripción completa

Detalles Bibliográficos
Autores principales: Roberts, Thomas C., Johansson, Henrik J., McClorey, Graham, Godfrey, Caroline, Blomberg, K. Emelie M., Coursindel, Thibault, Gait, Michael J., Smith, C.I. Edvard, Lehtiö, Janne, EL Andaloussi, Samir, Wood, Matthew J.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634378/
https://www.ncbi.nlm.nih.gov/pubmed/26385637
http://dx.doi.org/10.1093/hmg/ddv381