Structural Analysis of Monomeric RNA-Dependent Polymerases: Evolutionary and Therapeutic Implications

The crystal structures of monomeric RNA-dependent RNA polymerases and reverse transcriptases of more than 20 different viruses are available in the Protein Data Bank. They all share the characteristic right-hand shape of DNA- and RNA polymerases formed by the fingers, palm and thumb subdomains, and,...

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Detalles Bibliográficos
Autores principales: Jácome, Rodrigo, Becerra, Arturo, Ponce de León, Samuel, Lazcano, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634563/
https://www.ncbi.nlm.nih.gov/pubmed/26397100
http://dx.doi.org/10.1371/journal.pone.0139001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634563/
https://www.ncbi.nlm.nih.gov/pubmed/26397100
http://dx.doi.org/10.1371/journal.pone.0139001

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