An assessment of catalytic residue 3D ensembles for the prediction of enzyme function

BACKGROUND: The central element of each enzyme is the catalytic site, which commonly catalyzes a single biochemical reaction with high specificity. It was unclear to us how often sites that catalyze the same or highly similar reactions evolved on different, i. e. non-homologous protein folds and how...

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Detalles Bibliográficos
Autores principales: Žváček, Clemens, Friedrichs, Gerald, Heizinger, Leonhard, Merkl, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634577/
https://www.ncbi.nlm.nih.gov/pubmed/26538500
http://dx.doi.org/10.1186/s12859-015-0807-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634577/
https://www.ncbi.nlm.nih.gov/pubmed/26538500
http://dx.doi.org/10.1186/s12859-015-0807-6

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