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An assessment of catalytic residue 3D ensembles for the prediction of enzyme function
BACKGROUND: The central element of each enzyme is the catalytic site, which commonly catalyzes a single biochemical reaction with high specificity. It was unclear to us how often sites that catalyze the same or highly similar reactions evolved on different, i. e. non-homologous protein folds and how...
Autores principales: | Žváček, Clemens, Friedrichs, Gerald, Heizinger, Leonhard, Merkl, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634577/ https://www.ncbi.nlm.nih.gov/pubmed/26538500 http://dx.doi.org/10.1186/s12859-015-0807-6 |
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