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Arginase 1+ microglia reduce Aβ plaque deposition during IL-1β-dependent neuroinflammation
BACKGROUND: Neuroinflammation has long been considered a driver of Alzheimer’s disease progression. However, experiments developed to explore the interaction between neuroinflammation and Alzheimer’s disease (AD) pathology showed a surprising reduction in amyloid beta (Aβ) plaque deposition. We soug...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634600/ https://www.ncbi.nlm.nih.gov/pubmed/26538310 http://dx.doi.org/10.1186/s12974-015-0411-8 |