Arginase 1+ microglia reduce Aβ plaque deposition during IL-1β-dependent neuroinflammation

BACKGROUND: Neuroinflammation has long been considered a driver of Alzheimer’s disease progression. However, experiments developed to explore the interaction between neuroinflammation and Alzheimer’s disease (AD) pathology showed a surprising reduction in amyloid beta (Aβ) plaque deposition. We soug...

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Detalles Bibliográficos
Autores principales: Cherry, Jonathan D., Olschowka, John A., O’Banion, M. Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634600/
https://www.ncbi.nlm.nih.gov/pubmed/26538310
http://dx.doi.org/10.1186/s12974-015-0411-8

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