A Mouse Model That Reproduces the Developmental Pathways and Site Specificity of the Cancers Associated With the Human BRCA1 Mutation Carrier State

Predisposition to breast and extrauterine Müllerian carcinomas in BRCA1 mutation carriers is due to a combination of cell-autonomous consequences of BRCA1 inactivation on cell cycle homeostasis superimposed on cell-nonautonomous hormonal factors magnified by the effects of BRCA1 mutations on hormona...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Yen, Hai-Yun, Austria, Theresa, Pettersson, Jonas, Peti-Peterdi, Janos, Maxson, Robert, Widschwendter, Martin, Dubeau, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634618/
https://www.ncbi.nlm.nih.gov/pubmed/26629527
http://dx.doi.org/10.1016/j.ebiom.2015.08.034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634618/
https://www.ncbi.nlm.nih.gov/pubmed/26629527
http://dx.doi.org/10.1016/j.ebiom.2015.08.034

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