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Recombinant Receptor Binding Domain Protein Induces Partial Protective Immunity in Rhesus Macaques Against Middle East Respiratory Syndrome Coronavirus Challenge()

BACKGROUND: Development an effective vaccine against Middle East respiratory syndrome coronavirus (MERS-CoV) is urgent and limited information is available on vaccination in nonhuman primate (NHP) model. We herein report of evaluating a recombinant receptor-binding domain (rRBD) protein vaccine in a...

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Detalles Bibliográficos
Autores principales: Lan, Jiaming, Yao, Yanfeng, Deng, Yao, Chen, Hong, Lu, Guangwen, Wang, Wen, Bao, Linlin, Deng, Wei, Wei, Qiang, Gao, George F., Qin, Chuan, Tan, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634622/
https://www.ncbi.nlm.nih.gov/pubmed/26629538
http://dx.doi.org/10.1016/j.ebiom.2015.08.031