Iterative sub-network component analysis enables reconstruction of large scale genetic networks

BACKGROUND: Network component analysis (NCA) became a popular tool to understand complex regulatory networks. The method uses high-throughput gene expression data and a priori topology to reconstruct transcription factor activity profiles. Current NCA algorithms are constrained by several conditions...

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Detalles Bibliográficos
Autores principales: Jayavelu, Naresh Doni, Aasgaard, Lasse S., Bar, Nadav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634733/
https://www.ncbi.nlm.nih.gov/pubmed/26537518
http://dx.doi.org/10.1186/s12859-015-0768-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634733/
https://www.ncbi.nlm.nih.gov/pubmed/26537518
http://dx.doi.org/10.1186/s12859-015-0768-9

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