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Iterative sub-network component analysis enables reconstruction of large scale genetic networks
BACKGROUND: Network component analysis (NCA) became a popular tool to understand complex regulatory networks. The method uses high-throughput gene expression data and a priori topology to reconstruct transcription factor activity profiles. Current NCA algorithms are constrained by several conditions...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634733/ https://www.ncbi.nlm.nih.gov/pubmed/26537518 http://dx.doi.org/10.1186/s12859-015-0768-9 |