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Loss of Toll-Like Receptor 4 Function Partially Protects against Peripheral and Cardiac Glucose Metabolic Derangements During a Long-Term High-Fat Diet
Diabetes is a chronic inflammatory disease that carries a high risk of cardiovascular disease. However, the pathophysiological link between these disorders is not well known. We hypothesize that TLR4 signaling mediates high fat diet (HFD)-induced peripheral and cardiac glucose metabolic derangements...
Autores principales: | Jackson, Ellen E., Rendina-Ruedy, Elisabeth, Smith, Brenda J., Lacombe, Veronique A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634760/ https://www.ncbi.nlm.nih.gov/pubmed/26539824 http://dx.doi.org/10.1371/journal.pone.0142077 |
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