Mammalian prion protein (PrP) forms conformationally different amyloid intracellular aggregates in bacteria

BACKGROUND: An increasing number of proteins are being shown to assemble into amyloid structures that lead to pathological states. Among them, mammalian prions outstand due to their ability to transmit the pathogenic conformation, becoming thus infectious. The structural conversion of the cellular p...

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Detalles Bibliográficos
Autores principales: Macedo, Bruno, Sant’Anna, Ricardo, Navarro, Susanna, Cordeiro, Yraima, Ventura, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634817/
https://www.ncbi.nlm.nih.gov/pubmed/26536866
http://dx.doi.org/10.1186/s12934-015-0361-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634817/
https://www.ncbi.nlm.nih.gov/pubmed/26536866
http://dx.doi.org/10.1186/s12934-015-0361-y

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