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Mammalian prion protein (PrP) forms conformationally different amyloid intracellular aggregates in bacteria
BACKGROUND: An increasing number of proteins are being shown to assemble into amyloid structures that lead to pathological states. Among them, mammalian prions outstand due to their ability to transmit the pathogenic conformation, becoming thus infectious. The structural conversion of the cellular p...
Autores principales: | Macedo, Bruno, Sant’Anna, Ricardo, Navarro, Susanna, Cordeiro, Yraima, Ventura, Salvador |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634817/ https://www.ncbi.nlm.nih.gov/pubmed/26536866 http://dx.doi.org/10.1186/s12934-015-0361-y |
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