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The safety of liposome bupivacaine following various routes of administration in animals

BACKGROUND: This report presents results from four preclinical studies evaluating safety and pharmacokinetics (PKs) of liposome bupivacaine following intravascular (intravenous [IV], intra-arterial [IA]), epidural, and intrathecal administration in dogs. METHODS: Intravascular administration was ini...

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Detalles Bibliográficos
Autores principales: Joshi, Girish P, Patou, Gary, Kharitonov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634838/
https://www.ncbi.nlm.nih.gov/pubmed/26586964
http://dx.doi.org/10.2147/JPR.S85424