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Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection

Mechanisms of protective immunity to Staphylococcus aureus infection in humans remain elusive. While the importance of cellular immunity has been shown in mice, T cell responses in humans have not been characterised. Using a murine model of recurrent S. aureus peritonitis, we demonstrated that prior...

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Detalles Bibliográficos
Autores principales: Brown, Aisling F., Murphy, Alison G., Lalor, Stephen J., Leech, John M., O’Keeffe, Kate M., Mac Aogáin, Micheál, O’Halloran, Dara P., Lacey, Keenan A., Tavakol, Mehri, Hearnden, Claire H., Fitzgerald-Hughes, Deirdre, Humphreys, Hilary, Fennell, Jérôme P., van Wamel, Willem J., Foster, Timothy J., Geoghegan, Joan A., Lavelle, Ed C., Rogers, Thomas R., McLoughlin, Rachel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634925/
https://www.ncbi.nlm.nih.gov/pubmed/26539822
http://dx.doi.org/10.1371/journal.ppat.1005226