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Molecular Subtype-Specific Expression of MicroRNA-29c in Breast Cancer Is Associated with CpG Dinucleotide Methylation of the Promoter

Basal-like breast cancer is a molecularly distinct subtype of breast cancer that is highly aggressive and has a poor prognosis. MicroRNA-29c (miR-29c) has been shown to be significantly down-regulated in basal-like breast tumors and to be involved in cell invasion and sensitivity to chemotherapy. Ho...

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Detalles Bibliográficos
Autores principales: Poli, Elizabeth, Zhang, Jing, Nwachukwu, Chika, Zheng, Yonglan, Adedokun, Babatunde, Olopade, Olufunmilayo I., Han, Yoo-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634951/
https://www.ncbi.nlm.nih.gov/pubmed/26539832
http://dx.doi.org/10.1371/journal.pone.0142224