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Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality

The transcription factor NF-κB has been associated with a range of pathological conditions of the heart, mainly based on its function as a master regulator of inflammation and pro-survival factor. Here, we addressed the question what effects activation of NF-κB can have during murine heart developme...

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Detalles Bibliográficos
Autores principales: Kraut, Bärbel, Maier, Harald J., Kókai, Enikö, Fiedler, Katja, Boettger, Thomas, Illing, Annett, Kostin, Sawa, Walther, Paul, Braun, Thomas, Wirth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634958/
https://www.ncbi.nlm.nih.gov/pubmed/26539991
http://dx.doi.org/10.1371/journal.pone.0141591