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Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality
The transcription factor NF-κB has been associated with a range of pathological conditions of the heart, mainly based on its function as a master regulator of inflammation and pro-survival factor. Here, we addressed the question what effects activation of NF-κB can have during murine heart developme...
Autores principales: | Kraut, Bärbel, Maier, Harald J., Kókai, Enikö, Fiedler, Katja, Boettger, Thomas, Illing, Annett, Kostin, Sawa, Walther, Paul, Braun, Thomas, Wirth, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634958/ https://www.ncbi.nlm.nih.gov/pubmed/26539991 http://dx.doi.org/10.1371/journal.pone.0141591 |
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