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IMGT/HighV-QUEST Statistical Significance of IMGT Clonotype (AA) Diversity per Gene for Standardized Comparisons of Next Generation Sequencing Immunoprofiles of Immunoglobulins and T Cell Receptors

The adaptive immune responses of humans and of other jawed vertebrate species (gnasthostomata) are characterized by the B and T cells and their specific antigen receptors, the immunoglobulins (IG) or antibodies and the T cell receptors (TR) (up to 2.10(12) different IG and TR per individual). IMGT,...

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Detalles Bibliográficos
Autores principales: Aouinti, Safa, Malouche, Dhafer, Giudicelli, Véronique, Kossida, Sofia, Lefranc, Marie-Paule
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634997/
https://www.ncbi.nlm.nih.gov/pubmed/26540440
http://dx.doi.org/10.1371/journal.pone.0142353