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Quantifying and correcting for tail vein extravasation in small animal PET scans in cancer research: is there an impact on therapy assessment?

BACKGROUND: Tail vein injection under short anesthesia is the most commonly used route for administering radiopharmaceuticals. However, the small caliber of the vein in rodents may lead to tracer extravasation and thereby compromise quantitative accuracy of PET. We aimed to evaluate a method for cor...

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Detalles Bibliográficos
Autores principales: Lasnon, Charline, Dugué, Audrey Emmanuelle, Briand, Mélanie, Dutoit, Soizic, Aide, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635168/
https://www.ncbi.nlm.nih.gov/pubmed/26543028
http://dx.doi.org/10.1186/s13550-015-0141-z